Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
This study aimed to assess serum irisin level in myocardial infarction (MI) with or without heart failure (HF) and the possible relation between irisin and cardiac markers, tumor necrosis factor-α (TNF-α) and lipid profile.
|
30958967 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of IL-6, TNF-α, and inflammatory related molecules ICAM-1, VCAM-1, MMP-2 and -9, nuclear NF-kB, and iNOS, were elevated in MI-V.
|
30642049 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Serum levels of tumor necrosis factor (TNF) rise with aging and have been correlated with the incidence of myocardial infarction.
|
20421368 |
2010 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Moreover, S+MI group, but not S alone, showed a significant increase in the expression of connective tissue growth factor (CTGF) and fibrotic proteins fibronectin (FN) and <i>α</i>-smooth muscle actin (SMA), in comparison to controls, in addition to a significant increase in mRNA levels of IL-6 and TNF-<i>α</i> inflammatory markers.
|
29177025 |
2017 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, pretreated group showed decreased activation of TNF-α, Caspase-3 activity along with reduction in the myocardial infarct size.
|
31630586 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Notably, ACE2 overexpression significantly reduced the MI-induced increase in apoptosis, macrophage infiltration, and HMGB1 and proinflammatory cytokine expression (TNF-α and IL-6).
|
26498282 |
2016 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Gambogic acid suppressed the activation of interleukin (IL)-6 and tumor necrosis factor-α, and increased IL-10 levels in MI rats.
|
29434760 |
2018 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Dietary supplementation with flaxseed, ALA or SDG before and after the induction of the MI significantly reduced the incidence of arrhythmias and resulted in significantly smaller infarct size, less left ventricle dilation, and decreased myocardial fibrosis and tumor necrosis factor-α levels compared to the control MI group.
|
31284167 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
HSP70 levels were positively correlated with monocyte TLR4, plasma interleukin-6 and tumor necrosis factor-alpha levels in AMI patients.
|
16714144 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction.
|
16718633 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of TNF-alpha, iNOS, VEGF(164) and VEGF(188) was observed during the whole period after myocardial infarction (on days 1, 4, 11, 28 and 40), whereas VEGF(120) was found only on day 1 and 4.
|
11399901 |
2001 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The MI group showed higher levels of cardiac TNF-α compared to the MIL and MIT groups.
|
28599197 |
2017 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The immunohistochemical staining results showed that IL-6 knockout could lower the MI-induced high expression of TNF-α (p<0.05), and Masson's trichrome staining indicated that IL-6 knockout could also repress the degree of cardiac fibrosis.
|
31364133 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Phospholipase D1 is a regulator of tumor necrosis factor-α expression and release upon LPS-induced sepsis and following myocardial infarction (MI).
|
30555342 |
2018 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
Myocardial Infarction
|
0.600 |
PosttranslationalModification
|
disease |
BEFREE |
Atorvastatin can improve cardiac remodeling after myocardial infarction in rats, which may be associated with its inhibition of p38 phosphorylation and its decrease of TNF-α expression.
|
30116330 |
2018 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
CTD_human |
Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction.
|
16310260 |
2006 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
RGD |
Tumour necrosis factor-α and its receptors in the beneficial effects of vagal stimulation after myocardial infarction in rats.
|
21362018 |
2011 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The MI group produced a significant increase in myocardial infarct size, serum cardiac biomarkers (LDH and CK-MB), proinflammatory cytokines (TNF-α and IL-6), and MDA levels, and a significant decrease in SOD level compared with the sham group.
|
31280453 |
2019 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The probability of MI was lower in TNF inhibitor responders compared with non-responders (p = .001).
|
27881030 |
2018 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
In vivo, echocardiography was performed on rats with induced MI after their treatment with TNF-α and hypoxia-induced secretome.
|
29258676 |
2018 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Using a tumor necrosis factor (TNF)-α-induced bone marrow (BM)-MSC injury model in vitro and a rat MI model in vivo, we showed in the current study that miR-23a was involved in TNF-α-induced BM-MSC apoptosis through regulating caspase-7 and that the injection of BM-MSCs overexpressing miR-23a could improve left ventricular (LV) function and reduce infarct size in the rat MI model.
|
24269648 |
2014 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
We generated tDCs by treating bone marrow-derived dendritic cells with tumor necrosis factor-α and cardiac lysate from MI mice.
|
28174192 |
2017 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.
|
30953351 |
2019 |